Product Description

FGR Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-19870-60, E-AB-19870-120, E-AB-19870-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: FGR

Target Synonym: c fgr; c fgr protooncogene; c src 2 proto oncogene; c src2; Fgr; FGR; FLJ43153; Gardner Rasheed feline sarcoma viral (v fgr); Gardner Rasheed feline sarcoma viral (v fgr) oncogene homolog; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; MGC75096; p55 c fgr protein; P55 FGR; P55-FGR; p55c fgr; p58-Fgr; p58c fgr; p58c-Fgr; Proto oncogene c Fgr; Proto oncogene tyrosine protein kinase FGR; Proto-oncogene c-Fgr; SRC 2; SRC2; Tyrosine protein kinase Fgr; Tyrosine-protein kinase Fgr

Research Areas: Cancer, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P09769

Background: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Concentration: 2.04 mg/mL

Immunogen: Synthetic peptide of human FGR

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only