Fibrinogen Beta Monoclonal Antibody - BT-MCA0537

Fibrinogen Beta Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0537-50, BT-MCA0537-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Areas: Cardiovascular; Metabolism

Target Protein: FGB

Applications: WB, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Fibrinogen beta chain

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P02675; Mouse: Q8K0E8

Synonyms: FGB; Fibrinogen beta chain

GeneID: Human: 2244

Research Use Only