Fibulin 5 Monoclonal Antibody - BT-MCA4823

Fibulin 5 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4823-50, BT-MCA4823-100

Citations, Manuals and MSDS Available upon request.

Background: Fibulin 5(FBLN5), with 448-amino acid protein (about 50kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.

Research Areas: Others

Target Protein: Fibulin 5

Applications: IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3F10A5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: Fibulin 5

Immunogen: Purified recombinant fragment of Fibulin 5 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: Q9UBX5

Synonyms: EVEC, UP50, ARMD3, DANCE

GeneID: 10516

Research Use Only