FIG4 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A15372-20, A15372-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 104kDa
Observed Molecular Weight: 104kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 9896
SWISS: Q92562
Alternate Names: BOP; YVS; BTOP; SAC3; ALS11; CMT4J; KIAA0274; dJ249I4.1; FIG4
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:200 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Neuroscience, Neurodegenerative Diseases, Other Neurological disorders.
NCBI Alias: FIG4
Research Use Only