FKB1A Polyclonal Antibody - BT-AP15597

FKB1A Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15597-20, BT-AP15597-50, BT-AP15597-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.

Research Areas: Immunology

Target Protein: FKBP1A

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Peptidyl-prolyl cis-trans isomerase FKBP1A

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P62942; Mouse: P26883; Rat: Q62658

Synonyms: Peptidyl-prolyl cis-trans isomerase FKBP1A;PPIase FKBP1A;EC 5.2.1.8;12 kDa FK506-binding protein;12 kDa FKBP;FKBP-12;Calstabin-1;FK506-binding protein 1A;FKBP-1A;Immunophilin FKBP12

GeneID: Human: 2280

Research Use Only