FMR1 Monoclonal Antibody - BT-MCA4721

FMR1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4721-50, BT-MCA4721-100

Citations, Manuals and MSDS Available upon request.

Background: FMR1, also known as POF, FMRP, FRAXA. Entrez Protein: NP_002015. It is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.

Research Areas: Others

Target Protein: FMR1

Applications: IHC, ICC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 4G9

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: FMR1

Immunogen: Purified recombinant fragment of human FMR1 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 71kDa

UniProt Accession: Q06787

Synonyms: POF, FMRP, POF1, FRAXA

GeneID: 2332

Research Use Only