Product Description

FN3K Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES10651-50, ES10651-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. [provided by RefSeq, Feb 2012],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human protein. at AA range: 130-210

Isotype: IgG

Target: FN3K

Specificity: FN3K Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Widely expressed (PubMed:11522682), Expressed in erythrocytes (PubMed:11016445),

Observed Band (KD): 33kD

Function: Function: May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme
Similarity: Belongs to the fructosamine kinase family
Subunit: Monomer
Tissue Specificity: Expressed in erythrocytes

Subcellular Location: cytosol,

Storage and Stability: -20°C/1 year

Gene Name: FN3K

Protein Name: Fructosamine-3-kinase (EC 2.7.1.-)

Mouse SwissProt Number: Q9ER35

Research Use Only