FOXP2 Monoclonal Antibody - BT-MCA4745

FOXP2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4745-50, BT-MCA4745-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Research Areas: Epigenetics and nuclear signaling

Target Protein: FOXP2

Reactivity: Human

Clonality: Monoclonal

Clone ID: 5C11A8

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: FOXP2

Immunogen: Purified recombinant fragment of human MAPK3 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 85kDa

UniProt Accession: O15409

Synonyms: SPCH1, CAGH44, TNRC10, DKFZp686H1726

GeneID: 93986

Research Use Only