FOXP3 Monoclonal Antibody - BT-MCA3956

FOXP3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3956-50, BT-MCA3956-100

Citations, Manuals and MSDS Available upon request.

Background: FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.

Research Areas: Cell Biology

Target Protein: FOXP3

Reactivity: Human

Clonality: Monoclonal

Clone ID: 4C7

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: FOXP3

Immunogen: Purified recombinant fragment of human FOXP3 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 47.2kDa

UniProt Accession: Q9BZS1

Synonyms: JM2, AIID, IPEX, PIDX, XPID, DIETER, MGC141961, MGC141963, FOXP3

GeneID: 50943

Research Use Only