FPR2 Polyclonal Antibody - BT-AP15674

FPR2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15674-20, BT-AP15674-50, BT-AP15674-100

Citations, Manuals and MSDS Available upon request.

Background: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).,Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis.,

Research Areas: Cardiovascular; Signal transduction

Target Protein: FPR2

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: N-formyl peptide receptor 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P25090; Mouse: O88536

Synonyms: N-formyl peptide receptor 2;FMLP-related receptor I;FMLP-R-I;Formyl peptide receptor-like 1;HM63;Lipoxin A4 receptor;LXA4 receptor;RFP

GeneID: Human: 2358

Research Use Only