Product Description

FPRL2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES5366-50, ES5366-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: IF, ELISA

Alternate Names: FPR3, FPRH1, FPRL2, N-formyl peptide receptor 3, FMLP-related receptor II, FMLP-R-II, Formyl peptide receptor-like 2

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human FPRL2. AA range:304-353

Isotype: IgG

Target: FPRL2

Specificity: FPRL2 Polyclonal Antibody detects endogenous levels of FPRL2 protein.

Dilution: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Detected in various tissues with highest expression in lung,

Molecular Weight (Da): 40kD

Fields: Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection

Function: Function: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system
Similarity: Belongs to the G-protein coupled receptor 1 family

Subcellular Location: Cell membrane, Multi-pass membrane protein

Storage and Stability: -20°C/1 year

Gene Name: FPR3

Protein Name: N-formyl peptide receptor 3

Research Use Only