Product Description

Fumarase Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB65925-50, MB65925-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Fumarate hydratase (Fumarase, FH) is canonically regarded as a mitochondrial enzyme of the tricarboxylic acid cycle that catalyzes fumarate to malate. Studies have demonstrated that deficiencies in FH can lead to hereditary leiomyomatosis and renal cell cancer or, in homozygous germline mutations, severe neurological and muscμlar disorders. There also exists a cytosolic fumarase isoenzyme that is involved in DNA damage repair.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Mouse

Applications: WB, IF/ICC

Alternate Names: Fumarate hydratase mitochondrial, Fumarase

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence of human Fumarase. The exact sequence is proprietary.

Dilution: WB (1/1000 - 1/3000), IF/ICC (1/100 - 1/200)

Purification: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of Fumarase protein.

Molecular Weight: ~ 50 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P07954

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only