G6PD Monoclonal Antibody - BT-MCA0577

G6PD Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0577-50, BT-MCA0577-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.

Research Areas: Signal transduction; Cardiovascular; Metabolism

Target Protein: G6PD

Applications: WB, IHC-p, IF, FCM, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Glucose-6-phosphate 1-dehydrogenase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P11413

Synonyms: G6PD; Glucose-6-phosphate 1-dehydrogenase; G6PD

GeneID: Human: 2539

Research Use Only