Product Description

GABRA4 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-92556-60, E-AB-92556-120, E-AB-92556-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GABRA4

Target Synonym: GABRA4

Research Areas: Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P48169

Background: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human GABRA4

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 61kDa

Observed MW: 72kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only