Product Description

GAPDH Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65483M-50, BS65483M-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Loading Control Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellμlar proceses such as membrane fusion, microtubμle bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types. GAPDH molecμle is composed of four 36kDa subunits.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Rabbit

Host: Mouse

Applications: WB

Alternate Names: 38 kDa BFA-dependent ADP-ribosylation substrate, Aging-associated gene 9 protein, BARS-38, cb609, EC 1.2.1.12, G3PD, G3PDH, GAPD, Glyceraldehyde 3 phosphate dehydrogenase, Glyceraldehyde 3 phosphate dehydrogenase liver, Glyceraldehyde 3 phosphate dehydrogenase muscle, KNC-NDS6, MGC102544, MGC102546, MGC103190, MGC103191, MGC105239, MGC127711, MGC88685, OCAS, p38 component, OCT1 coactivator in S phase, 38-KD component, wu:fb33a10.

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Fμll length GAPDH protein purified from rabbit muscle

Dilution: WB=1:1000-5000

Purification: affinity purified by Protein G

Specificity: GAPDH Monoclonal Antibody detects endogenous levels of GAPDH protein.

Molecular Weight: 38kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P46406

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only