Product Description

GAPDH Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4853-50, BT-MCA4853-100

Citations, Manuals and MSDS Available upon request.

Background: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. It catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Besides its functioning as a glycolytic enzyme in cytoplasm, recent evidence suggest that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of findings appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age- related neuronal diseases, such as Alzheimer

Research Areas: Others

Target Protein: GAPDH

Applications: WB, IHC, ICC

Reactivity: Human, Mouse, Rat

Clonality: Monoclonal

Clone ID: 1A10

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: GAPDH

Immunogen: Purified recombinant fragment of human GAPDH expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 37kDa

UniProt Accession: P04406

Synonyms: G3PD, GAPD, MGC88685

GeneID: 2597

Research Use Only