GATA-4 Monoclonal Antibody - BT-MCA0610

GATA-4 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0610-50, BT-MCA0610-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants.

Research Areas: Epigenetics and nuclear signaling; Stem cells; Developmental biology; Cancer; Cardiovascular

Target Protein: GATA4

Applications: WB, ELISA

Reactivity: Human,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Transcription factor GATA-4

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P43694; Mouse: Q08369

Synonyms: GATA4; Transcription factor GATA-4; GATA-binding factor 4

GeneID: Human: 2626; Mouse: 14463

Research Use Only