Product Description

GBP2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES10690-50, ES10690-100

Lead times: approximately 7-10 business days, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human protein . at AA range: 160-240

Isotype: IgG

Target: GBP2,

Specificity: GBP2 Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formulation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Foreskin, Lung, Skin, Spinal cord, Thymus,

Observed Band (KD): 65kD

Fields: NOD-like receptor signaling pathway

Function: Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. induction:By interferon gamma during macrophage activation. Similarity: Belongs to the GBP family.

Subcellular Location: Cytoplasm Cytoplasm, perinuclear region Golgi apparatus membrane Membrane, Lipid-anchor Cytoplasmic vesicle GBP2-GBP5 dimers localize to the Golgi apparatus.

Storage and Stability: -20°C/1 year

Gene Name: GBP2

Protein Name: Interferon-induced guanylate-binding protein 2, GTP-binding protein 2, GBP-2, HuGBP-2, Guanine nucleotide-binding protein 2

Human Gene ID: 2634

Human SwissProt Number: P32456

Mouse SwissProt Number: Q9Z0E6

Rat SwissProt Number: Q63663

Research Use Only