GCG Monoclonal Antibody - BT-MCA3160

GCG Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3160-50, BT-MCA3160-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.Tissue specificity: Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain.

Research Areas: Neuroscience

Target Protein: GCG

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2F9

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: GCG

Immunogen: Purified recombinant fragment of human GCG expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 21kDa

UniProt Accession: P01275

Synonyms: GLP1, GLP2, GRPP, GCG

GeneID: 2641

Research Use Only