GCKR Polyclonal Antibody - BT-AP03507

GCKR Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP03507-20, BT-AP03507-50, BT-AP03507-100

Citations, Manuals and MSDS Available upon request.

Background: GCKR encodes glucokinase regulator belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

Research Areas: Signal Transduction; Metabolism

Target Protein: GCKR

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: GCKR Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 68685

UniProt Accession: Human: Q14397; Mouse: Q91X44; Rat: Q07071

Synonyms: GCKR; Glucokinase regulatory protein; Glucokinase regulator

GeneID: Human: 2646; Mouse: 231103; Rat: 25658

Research Use Only