GCSm-Gamma Polyclonal Antibody - BT-AP03523

GCSm-Gamma Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP03523-20, BT-AP03523-50, BT-AP03523-100

Citations, Manuals and MSDS Available upon request.

Background: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Areas: Neuroscience

Target Protein: GCLM

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat, Monkey

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: GCSm-gamma Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 30727

UniProt Accession: Human: P48507; Mouse: O09172; Rat: P48508

Synonyms: GCLM; GLCLR; Glutamate--cysteine ligase regulatory subunit; GCS light chain; Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Glutamate--cysteine ligase modifier sub

GeneID: Human: 2730; Mouse: 14630; Rat: 29739

Research Use Only