GFRA2 Polyclonal Antibody - BT-AP09477

GFRA2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09477-20, BT-AP09477-50, BT-AP09477-100

Citations, Manuals and MSDS Available upon request.

Background: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Neuroscience

Target Protein: GFRA2

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: GDNF family receptor alpha-2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O00451; Mouse: O08842

Synonyms: GDNF family receptor alpha-2;GDNF receptor alpha-2;GDNFR-alpha-2;GFR-alpha-2;GDNF receptor beta;GDNFR-beta;Neurturin receptor alpha;NRTNR-alpha;NTNR-alpha;RET ligand 2;TGF-beta-rela

GeneID: Human: 2675

Research Use Only