GITR Monoclonal Antibody - BT-MCA4444

GITR Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4444-50, BT-MCA4444-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Research Areas: Others

Target Protein: GITR

Applications: FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 6H8B9

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: GITR

Immunogen: Purified recombinant fragment of human GITR (AA: 184-241) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 26kDa

UniProt Accession: Q9Y5U5

Synonyms: TNFRSF18, AITR, CD357, GITR-D

GeneID: 8784

Research Use Only