GKLF Monoclonal Antibody - BT-MCA0622

GKLF Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0622-50, BT-MCA0622-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Areas: Epigenetics and nuclear signaling; Stem cells; Developmental biology; Cancer; Cardiovascular

Target Protein: KLF4

Applications: WB, IHC-p, IF, ICC, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Krueppel-like factor 4

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O43474; Mouse: Q60793

Synonyms: KLF4; EZF; GKLF; Krueppel-like factor 4; Epithelial zinc finger protein EZF; Gut-enriched krueppel-like factor

GeneID: Human: 9314

Research Use Only