GLI-1 Polyclonal Antibody - BT-AP15737

GLI-1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15737-20, BT-AP15737-50, BT-AP15737-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Cancer; Epigenetics and nuclear signaling; Neuroscience; Stem cells

Target Protein: GLI1

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: GLI-1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P08151; Mouse: P47806

Synonyms: GLI-1; Zinc finger protein GLI1; Glioma-associated oncogene; Oncogene GLI

GeneID: Human: 2735; Mouse: 14632

Research Use Only