GLP Monoclonal Antibody - BT-MCA3168

GLP Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3168-50, BT-MCA3168-100

Citations, Manuals and MSDS Available upon request.

Background: Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.

Research Areas: Others

Target Protein: GLP

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1B7B4

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: GLP

Immunogen: Purified recombinant fragment of GLP expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: Q9H9B1

Synonyms: GLP

GeneID: 79813

Research Use Only