Product Description

GLRX1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15740-20, BT-AP15740-50, BT-AP15740-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimerandapos;s disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Research Areas: Cell biology; Metabolism

Target Protein: GLRX

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Glutaredoxin-1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P35754; Mouse: Q9QUH0; Rat: Q9ESH6

Synonyms: Glutaredoxin-1;Thioltransferase-1;TTase-1

GeneID: Human: 2745

Research Use Only