GlyRBeta Polyclonal Antibody - BT-AP03615

GlyRBeta Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP03615-20, BT-AP03615-50, BT-AP03615-100

Citations, Manuals and MSDS Available upon request.

Background: GLRB encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

Research Areas: Others

Target Protein: GLRB

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: GlyRbeta Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 56122

UniProt Accession: Human: P48167; Mouse: P48168; Rat: P20781

Synonyms: GLRB; Glycine receptor subunit beta; Glycine receptor 58 kDa subunit

GeneID: Human: 2743; Mouse: 14658; Rat: 25456

Research Use Only