GMNN Monoclonal Antibody - BT-MCA2614

GMNN Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2614-50, BT-MCA2614-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.

Research Areas: Others

Target Protein: GMNN

Applications: IHC, FCM

Reactivity: Human, Rat

Clonality: Monoclonal

Clone ID: 2H10G3

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: GMNN

Immunogen: Purified recombinant fragment of human GMNN (AA: FULL 1-209) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 23.6KDa

UniProt Accession: O75496

Synonyms: Gem, MGORS6

GeneID: 51053

Research Use Only