GNA11 Polyclonal Antibody - BT-AP15752

GNA11 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15752-20, BT-AP15752-50, BT-AP15752-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.

Research Areas: Signal transduction

Target Protein: GNA11

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Guanine nucleotide-binding protein subunit alpha-11

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P29992; Mouse: P21278; Rat: Q9JID2

Synonyms: Guanine nucleotide-binding protein subunit alpha-11;G alpha-11;G-protein subunit alpha-11;Guanine nucleotide-binding protein G;y subunit alpha

GeneID: Human: 2767

Research Use Only