GNAS3 Polyclonal Antibody - BT-AP15754

GNAS3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15754-20, BT-AP15754-50, BT-AP15754-100

Citations, Manuals and MSDS Available upon request.

Background: This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5andapos; exons. Some transcripts contain a differentially methylated region (DMR) at their 5andapos; exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key

Research Areas: Cancer; Metabolism; Signal transduction

Target Protein: GNAS

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Neuroendocrine secretory protein 55

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O95467; Mouse: Q9Z0F1; Rat: Q792G6

Synonyms: Neuroendocrine secretory protein 55;NESP55 [Cleaved into: LHAL tetrapeptide; GPIPIRRH peptide]

GeneID: Human: 2778

Research Use Only