GP6 Polyclonal Antibody - E-AB-19916

GP6 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-19916-60, E-AB-19916-120, E-AB-19916-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GP6

Target Synonym: Glycoprotein 6; Glycoprotein VI; GP6; GPIV; GPVI; GPVI; MGC138168; Platelet collagen receptor; Platelet glycoprotein VI; Platelet glycoprotein VI precursor

Research Areas: Cardiovascular

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9HCN6

Background: This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Concentration: 1.14 mg/mL

Immunogen: Synthetic peptide of human GP6

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only