GPC3 Monoclonal Antibody - BT-MCA2483

GPC3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2483-50, BT-MCA2483-100

Citations, Manuals and MSDS Available upon request.

Background: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Research Areas: Stem Cells

Target Protein: GPC3

Applications: WB, IHC, FCM

Clonality: Monoclonal

Clone ID: 2C7E9

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: GPC3

Immunogen: Purified recombinant fragment of human GPC3 (AA: 359-554) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 65.5kDa

UniProt Accession: P51654

Synonyms: SGB, DGSX, MXR7, SDYS, SGBS, OCI-5, SGBS1, GTR2-2

GeneID: 2719

Research Use Only