Product Description

GPM6A Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-63925-60, E-AB-63925-120, E-AB-63925-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GPM6A

Target Synonym: GPM6A; GPM6; M6A

Research Areas: Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P51674

Background: Neuronal membrane glycoprotein M6-ais aproteinthat in humans is encoded by theGPM6Agene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human GPM6A (NP_005268.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Calculated MW: 29kDa/30kDa/31kDa

Observed MW: 31kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only