Product Description

GPR75 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES4573-50, ES4573-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 2002],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IF, ELISA

Alternate Names: GPR75, Probable G-protein coupled receptor 75

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human GPR75. AA range:381-430

Isotype: IgG

Target: GPR75

Specificity: GPR75 Polyclonal Antibody detects endogenous levels of GPR75 protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium, In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer, Also expressed by islet cells (at protein level),

Observed Band (KD): 59kD

Function: Function: Orphan receptor
Similarity: Belongs to the G-protein coupled receptor 1 family
Tissue Specificity: Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer

Subcellular Location: Cell membrane, Multi-pass membrane protein

Storage and Stability: -20°C/1 year

Gene Name: GPR75

Protein Name: Probable G-protein coupled receptor 75

Mouse Gene ID: 237716

Mouse SwissProt Number: Q6X632

Research Use Only