Product Description

GPT2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-19961-60, E-AB-19961-120, E-AB-19961-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GPT2

Target Synonym: AAT2; Alanine aminotransferase 2; ALAT2; ALT2; Glutamate pyruvate transaminase 2; Glutamic alanine transaminase 2; Glutamic pyruvate transaminase (alanine aminotransferase) 2; Glutamic pyruvic transaminase 2; Glutamic--alanine transaminase 2; Glutamic--pyruvic transaminase 2; GPT 2; gpt2

Research Areas: Cancer, Metabolism, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q8TD30

Background: This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants.

Concentration: 2.16 mg/mL

Immunogen: Synthetic peptide of human GPT2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:25-1:100, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only