GROAlpha Polyclonal Antibody - BT-AP09755

GROAlpha Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09755-20, BT-AP09755-50, BT-AP09755-100

Citations, Manuals and MSDS Available upon request.

Background: This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.

Research Areas: Neuroscience; Signal transduction; Stem cells; Immunology

Target Protein: CXCL1

Applications: IHC-p, IF, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Growth-regulated alpha protein

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P09341; Mouse: P12850

Synonyms: Growth-regulated alpha protein;C-X-C motif chemokine 1;GRO-alpha;1-73;Melanoma growth stimulatory activity;MGSA;Neutrophil-activating protein 3;NAP-3 [Cleaved into: GRO-alpha;4-73; GRO-a; Growth-regulated alpha protein; C-X-C motif chemokine 1; GRO-alpha;1-73; Melanoma growth stimulatory activity; MGSA; Neutrophil-activating protein 3; NAP-3; GRO-alpha;4-73; GRO-alpha;5-73; GRO-alpha;6-73;

GeneID: Human: 2919; Mouse: 14825

Research Use Only