GSK3Beta Monoclonal Antibody - BT-MCA0636

GSK3Beta Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0636-50, BT-MCA0636-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Areas: Signal transduction; Stem cells; Cancer; Cardiovascular; Neuroscience; Metabolism

Target Protein: GSK3B

Applications: WB, IHC-p, IF, ICC, FCM, ELISA

Reactivity: Human,Mouse,Rat,Monkey

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Glycogen synthase kinase-3 beta

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P49841; Mouse: Q9WV60; Rat: P18266

Synonyms: GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine; threonine-protein kinase GSK3B

GeneID: Human: 2942; Mouse: 56637; Rat: 84027

Research Use Only