GSTM2 Polyclonal Antibody - BT-AP09776

GSTM2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09776-20, BT-AP09776-50, BT-AP09776-100

Citations, Manuals and MSDS Available upon request.

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individualandapos;s susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Research Areas: Metabolism; Signal transduction

Target Protein: GSTM2

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Glutathione S-transferase Mu 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P28161; Mouse: P15626; Rat: P08010

Synonyms: Glutathione S-transferase Mu 2;EC 2.5.1.18;GST class-mu 2;GSTM2-2

GeneID: Human: 2946

Research Use Only