GSTM2 Polyclonal Antibody - E-AB-18062

GSTM2 Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-18062-60, E-AB-18062-120, E-AB-18062-200 Citations, Manuals and MSDS Available upon request. Abbreviation: GSTM2 Target Synonym: Glutathione S alkyltransferase M2; Glutathione S aralkyltransferase M2; Glutathione S aryltransferase M2; Glutathione S transferase 4; Glutathione S transferase M1; Glutathione S transferase M2 (muscle); Glutathione S transferase Mu 2 (muscle); Glutathione S transferase Mu 2; Glutathione S-transferase Mu 2; GST class mu 2; GST class-mu 2; GST muscle; GST4; GSTM; GSTM2; GSTM2-2; GSTM2; GTHMUS; MGC117303; S (hydroxyalkyl)glutathione lyase M2 Research Areas: Metabolism, Signal Transduction Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human Application: IHC, ELISA Isotype: IgG Clonality: Polyclonal UNIProt ID: P28161 Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Concentration: 1.44 mg/mL Immunogen: Synthetic peptide of human GSTM2 Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 Purification Method: Antigen affinity purification Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000 Storage: -20°C/One year. Avoid freeze / thaw cycles. Shipping: Ice bag Research Use Only