Product Description

GUC2B Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15806-20, BT-AP15806-50, BT-AP15806-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys.

Research Areas: Signal transduction

Target Protein: GUCA2B

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Guanylate cyclase activator 2B [Cleaved into: Guanylate cyclase C-activating peptide 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q16661; Mouse: O09051; Rat: P70668

Synonyms: Guanylate cyclase activator 2B [Cleaved into: Guanylate cyclase C-activating peptide 2;Guanylate cyclase C-activating peptide II;GCAP-II; Uroguanylin;UGN]

GeneID: Human: 2981

Research Use Only