HAP1 Polyclonal Antibody - BT-AP09814

HAP1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09814-20, BT-AP09814-50, BT-AP09814-100

Citations, Manuals and MSDS Available upon request.

Background: Huntingtonandapos;s disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Research Areas: Cardiovascular; Epigenetics and nuclear signaling; Cancer; Cell biology; Metabolism; Neuroscience; Signal transduction

Target Protein: HAP1

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Huntingtin-associated protein 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P54257; Mouse: O35668; Rat: P54256

Synonyms: Huntingtin-associated protein 1;HAP-1;Neuroan 1

GeneID: Human: 9001

Research Use Only