HAT1 Polyclonal Antibody - BT-AP03892

HAT1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP03892-20, BT-AP03892-50, BT-AP03892-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by HAT1 (histone acetyltransferase 1)is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for HAT1.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: HAT1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: HAT1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 49513

UniProt Accession: Human: O14929; Mouse: Q8BY71; Rat: Q5M939

Synonyms: HAT1; KAT1; Histone acetyltransferase type B catalytic subunit; Histone acetyltransferase 1

GeneID: Human: 8520; Mouse: 107435; Rat: 296501

Research Use Only