HBA Polyclonal Antibody - BT-AP09821

HBA Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09821-20, BT-AP09821-50, BT-AP09821-100

Citations, Manuals and MSDS Available upon request.

Background: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5andapos;- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3andapos;. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5andapos; untranslated regions and the introns, but they differ significantly over the 3andapos; untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

Research Areas: Cardiovascular; Signal transduction

Target Protein: HBA1;

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Hemoglobin subunit alpha

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P69905; Mouse: P01942; Rat: P01946

Synonyms: Hemoglobin subunit alpha;Alpha-globin;Hemoglobin alpha chain

GeneID: Human: 3039

Research Use Only