HBsAg Antibody
Sizes: 100μg, 1mg
Catalogue Numbers: HBV001-100, HBV001-1
Citations, Manuals and MSDS Available upon request.
Target: HBsAg
Form: Liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: Monoclonal
Clone ID: 4A10
Isotype: IgG2a
Storage: 20mM PBS, 0.1% proclin300, store at 2-8°C up to 21 days, -20°C for
long-term storage. Don't repeated freeze-thaw.
Background: The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assumes fusion between virion membrane and endosomal membrane (Probable). In its internal conformation the protein plays a role in virion morphogenesis and mediates the contact with the nucleocapsid like a matrix protein.
Immunogen: HBsAg
Synonyms: Large envelope protein|Large surface protein|Large S protein|Major surface antigen
Observed Molecular Weight: 43 kDa
Reactivity: Human
Tested Application: ELISA, test strip
Research Area: Signal Transduction
Research Use Only