HCN4 Polyclonal Antibody - BT-AP09844

HCN4 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09844-20, BT-AP09844-50, BT-AP09844-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15.

Research Areas: Cardiovascular; Neuroscience

Target Protein: HCN4

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9Y3Q4; Mouse: O70507; Rat: Q9JKA7

Synonyms: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

GeneID: Human: 10021

Research Use Only