HDAC3 Monoclonal Antibody - BT-MCA3164

HDAC3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3164-50, BT-MCA3164-100

Citations, Manuals and MSDS Available upon request.

Background: HDAC3: histone deacetylase 3, also known as HD3, RPD3, RPD3-2. Entrez Protein NC_000005. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: HDAC3

Applications: IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3A7B5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: HDAC3

Immunogen: Purified recombinant fragment of HDAC3 (aa224-428) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 48.8kDa

UniProt Accession: O15379

Synonyms: HD3, RPD3, RPD3-2

GeneID: 8841

Research Use Only