HDAC4 Monoclonal Antibody - BT-MCA0671

HDAC4 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0671-50, BT-MCA0671-100

Citations, Manuals and MSDS Available upon request.

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Research Areas: Epigenetics and nuclear signaling; Stem cells; Cardiovascular

Target Protein: HDAC4

Applications: WB, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Histone deacetylase 4

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P56524; Mouse: Q6NZM9

Synonyms: HDAC4; KIAA0288; Histone deacetylase 4; HD4

GeneID: Human: 9759

Research Use Only