HDAC4 Monoclonal Antibody - BT-MCA2920

HDAC4 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2920-50, BT-MCA2920-100

Citations, Manuals and MSDS Available upon request.

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: HDAC4

Applications: WB

Reactivity: Human

Clonality: Monoclonal

Clone ID: 7B2

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: HDAC4

Immunogen: Purified recombinant fragment of human HDAC4 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS containing 0.05% sodium azide.

Molecular Weight (Da): 119kDa

UniProt Accession: P56524

Synonyms: HD4, HDACA, HA6116, HDAC-A, KIAA0288, HDAC4

GeneID: 9759

Research Use Only