HEPS Polyclonal Antibody - BT-AP09867

HEPS Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09867-20, BT-AP09867-50, BT-AP09867-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with the growth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serine protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternative splicing results in multiple transcript variants.

Research Areas: Cancer; Cell biology; Signal transduction

Target Protein: HPN

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Serine protease hepsin

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P05981; Mouse: O35453; Rat: Q05511

Synonyms: Serine protease hepsin;EC 3.4.21.106;Transmembrane protease serine 1 [Cleaved into: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain]

GeneID: Human: 3249

Research Use Only